In the two cases, build-up of PcG scars at promoters correlated using amount of gene silencing (Fig EV5F)
At long last, we desired to explore the partnership between PcG recruitment at marketers and initiation of X-linked gene silencing, given the small enrichment of PcG markings over some X-linked family genes in Xist I”B+C-induced tissue (Fig 3B and C)
- A. Genome browser plots showing RNA-seq reads on Xist/Tsix family genes for Xist FL, Xist I”A, and Xist I”B+C mutants in DOX and noDOX problems at day 2 of distinction; yellowish cardboard boxes highlight the deleted parts both in Xist I”A and Xist I”B+C.
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